Florabella®

What causes wrinkles? All evidence points to glycation — the process by which a protein molecule unhealthily crosslinks with a sugar molecule. Glycation creates advanced glycation end products, or AGEs for short. AGEs speed up oxidative damage, especially to connective tissues such as collagen and elastin, and this damage leads to skin wrinkling.[i],[ii],[iii]

Named after a beautiful Japanese goddess, sakura extract is a unique ingredient manufactured from cherry blossoms through a proprietary process. This proprietary nutricosmetic has been shown to inhibit the production of AGEs, and thus holds great promise for oral beauty care products.*

A double-blind, placebo-controlled human clinical trial of 20 women aged 30-50 found that sakura extract [iv]:

  • Significantly reduces AGE production*
  • Maintains skin elasticity*
  • Reduces skin moisture loss*
  • Increases skin smoothness*
  • Reduces pore size*
  • Evens the complexion, minimizing brown spots and redness*

 

STATUS

FUNCTIONS

Healthy Aging

Cherry Blossom - Maypro

      MECHANISM OF ACTION

      Research in normal human fibroblasts found that sakura extract (in particular, its two bioactive components: caffeoyl glucose and quercetin glucoside) inhibits the production of AGEs in a dose-dependent fashion.[v] In addition, sakura extract preserves the longevity of fibroblasts and promotes the production of collagen and the formation of collagen lattice.*[vi]

      SAFETY

      Cherry blossoms are edible and are used as a food ingredient in Japan, especially as part of spring celebrations. Sakura extract has been tested for the presence of pesticides, toxicity, mutagenesis, and skin and eye irritation and has been found to be highly safe.

      [i] Repinski, K. Prevention. 2011 Nov. http://www.prevention.com/beauty/beauty/how-sugar-ages-your-skin[ii] Gkogkolou P, Böhm M. Dermatoendocrinol. 2012 Jul 1;4(3):259-70.

      [iii] Dyer DG, et al. J Clin Invest. 1993: 19:2463-9.

      [iv] Unpublished study. Committee of Sacred Heart Association, Platinum Health Clinic for Corporate Executive.  Research and Development Department, Oryza Oil and Fat Chemical Company, Ltd. 2011.

      [v] Unpublished study. Committee of Sacred Heart Association, Platinum Health Clinic for Corporate Executive.  Research and Development Department, Oryza Oil and Fat Chemical Company, Ltd. 2011.

      [vi] Unpublished study. Committee of Sacred Heart Association, Platinum Health Clinic for Corporate Executive.  Research and Development Department, Oryza Oil and Fat Chemical Company, Ltd. 2011.