Increasingly, scientists who study aging have focused their attention on a group of protective genes called sirtuins, especially SIRT1 (known as “the longevity gene”). SIRT1 “recharges” mitochondria — the “power plants” of the cells — which tend to wind down with age. Therefore, any substance that can enhance the SIRT1 gene pathway is of great interest to anti-aging researchers.
Resveratrol is well-known for this effect. Now, there’s another natural ingredient that works in the same way, but is five times more potent (See graph below): Sirtmax®. Derived from the rhizome of black turmeric (Kaempferia parviflora) and rich in polymethoxyflavonoids, Sirtmax® could be the anti-aging ingredient you’re looking for.
A double-blind, placebo-controlled human study with 27 subjects found that taking 100 mg of Sirtmax® daily for seven weeks:
- Caused a reduction in body weight*
- Helped maintain blood sugar levels already within a normal range*
- Decreased the production of advanced glycation end products (AGES)
- Showed a trend toward improvement in arterial flexibility*
Mechanism of Action
Animal and in vitro research has shown that black turmeric inhibits pancreatic lipase (a fat-digesting enzyme) and glycation, a reaction that can cause oxidative damage., In addition, it has a favorable impact on adipogenesis (fat cell differentiation) and the secretion of adiponectin, which regulates glucose levels.
Black turmeric is related to both turmeric and ginger. One of the most popular herbal medicines in Thailand and Laos, it has been safely consumed as a revitalizing drink for years. A double-blind, placebo-controlled human study on Sirtmax® found no adverse effects.